Endocrine Abstracts

Aim: To study clinical presentation peculiarities of constitutional puberty delay in boys.Materials and methods: We examined 54 boys (mean age 13.8 years) with constitutional puberty delay (CPD). All examinees underwent general clinical examination as well as biochemical and hormonal investigations (levels of GH, LH, FSH, free testosterone, prolactin, cortisol, TSH, etc.), having their bone age and anthropometric parameters by Tanner-Whitehouse measured ...

Objective: To investigate frequency of secondary GH deficit (SGHD) in patients with acromegaly in the Republic of Uzbekistan (RUz).Material and methods: There are 366 patients with acromegaly registered in RUz. We observed 15 patients with acromegaly with SGHD, among them 3 male and 12 female with middle age 51.6 years. All patients undergone following tests: pituitary hormones levels (GH, IGF1, ACTH, prolactin, TSH, FSH, LH, etc.), blood glucose, bioche...

Aim: To study significance of risk factors in puberty delay in boys.Materials and methods: We examined 54 boys (mean age 13.8 years) with constitutional puberty delay (CPD). All examinees underwent general clinical examination as well as biochemical and hormonal investigations (levels of GH, LH, FSH, free testosterone, prolactin, cortisol, TSH, etc.), having their bone age and anthropometric parameters by Tanner-Whitehouse measured and their sexual devel...

Aim: To study physical, sexual and mental development and neurophychological disorders of children with congenital hypothyroidism.Methods and materials: 11.5±0.5 year old 60 children and teenagers with congenital hypothyroidism (CH) have been examined. Radioimmunologic (RIA) study of blood hormone level revealed confident decrease of somatotropic hormone (STH), thyroid (T3, T4), gonadotropic, sex hormones and increase of thyreotropic hormone (TTG). ...

Aim: to study features of growth and development in teenagers with Diabetes Insipidus of central genesis.Material and methods: During 2009–2010 years we examined 37 teenagers with Diabetes Insipidus of central genesis. 19 boys (51.3%) and 18 girls (48.6%) among them. Mean age of boys and girls was 13.5 years.All patients underwent general clinical examination. Levels of STH, LH, FSH, prolactin, TSH, free thyroxin, cortisol, et...

Aim: To study clinical–epidemiological peculiarities of diabetic macroangiopathies in diabetes mellitus (DM) and diabetes insipidus (DI) combination.Materials and methods: We examined 2208 cases of DI registered in the RUz in 2006–2010, 106 DM–DI combinations among them. DM–DI combination prevalence, calculated for 100 000 of adult and infant population, was assessed analysis of data on patients registered at the endocrine ambulances....

Aim: To study character of macrovascular complications in combination of diabetes mellitus (DM) and diabetes insipidus (DI).Materials and methods: Within the period from 2006 to 2010, we examined 2208 cases of DI among them 106 DM–DI combinations. The patients had their endocrine and neurologic statuses assessed with blood and urine density investigation, including complete urinalysis and Zimnitskyi urine count, RIA and measurement of pituitary horm...